The Philadelphia Eagles are set to host the San Francisco 49ers on Sunday, January 11, 2026, in a crucial NFC Wild Card match at Lincoln Financial Field. This rematch features the Eagles, who finished the regular season with an 11-6 record and hold the No. 3 seed, against a 49ers team that boasts a 12-5 record and has won six of its last seven games, with quarterback Brock Purdy leading the charge.
Philadelphia has received a significant boost ahead of the game. All-Pro right tackle Lane Johnson has practiced for three consecutive days, indicating a potential return to an otherwise healthy lineup. In contrast, the 49ers are grappling with a more precarious injury situation. Star left tackle Trent Williams is listed as questionable due to a hamstring injury, while wide receiver Ricky Pearsall is also facing uncertainty with knee and ankle issues. The absence of Williams has had a notable impact on San Francisco’s rushing performance, which has averaged just 2.8 yards per carry to the left side of the offensive line.
This disparity in team health has led analysts to reevaluate their projections for the game. The latest simulations have incorporated the injury reports and the respective strengths of both teams to provide insights into the matchup.
Latest Betting Insights
According to Dimers.com, a leader in sports betting predictions, the current odds for the 49ers vs. Eagles matchup reflect the shifting dynamics. As of now, the Eagles are favored to win with a 69% chance of victory, while the 49ers have a 54% likelihood of covering the spread at +6. The over/under for the game is set at 44.5, with a balanced prediction of hitting at a 50-50 rate.
For those looking to place bets, the current spread shows the 49ers at +6 (-110) and the Eagles at -6 (-108). The moneyline stands at 49ers +225 and Eagles -265, illustrating the Eagles’ status as the favorites. These odds are subject to change as the game approaches.
Expert Predictions and Player Prop Bets
Dimers’ advanced data analysis has generated predictions based on 10,000 simulations of the game. The predicted final score suggests the Eagles will triumph with a score of 24-19. This projection draws on both teams’ average scores throughout the simulations, providing a glimpse into potential outcomes.
Additionally, player prop bets offer an exciting avenue for fans looking to wager on specific performances rather than the overall game outcome. For the 49ers, the probabilities for first touchdown scorers include Christian McCaffrey at 13.9% and George Kittle at 6.5%. For anytime touchdowns, McCaffrey holds a strong 58.3% chance, followed by Kittle at 33.6%.
On the Eagles’ side, Saquon Barkley leads the first touchdown scorer predictions with an 11.4% probability, while quarterback Jalen Hurts follows at 9.9%. Barkley also has an impressive 48.7% chance of scoring at any time during the game.
As fans gear up for this high-stakes Wild Card encounter, the anticipation continues to build. The game will kick off at 4:30 p.m. EST, presenting an exciting opportunity for both teams to advance in the playoffs.
Engaging in sports betting comes with its own set of responsibilities. It is essential to practice responsible gambling and consult reputable sources for the latest information. With the Eagles and 49ers set to face off, fans are eager to see how the game unfolds and which team will secure a spot in the next round of the playoffs.
